Comparison of bioconcentration and kinetics of GenX in tilapia Oreochromis mossambicus in fresh and brackish water

Contaminants of emerging concern (CEC) are a broad suite chemicals commonly found in the environment, aquatic organisms and even drinking water. They include pharmaceuticals, personal care products, industrial compounds added to consumer products. The CEC ammonium 2,3,3,3-tetrafluoro-2-heptafluoropropoxy propanoic acid, which is more known as generic name GenX, replacement common processing aid longer chain perfluorinated (PFAS) due manufacturing shift 2002 following EPA stewardship program 2015/16 USA (USEPA, 2006). However, recently reported North Carolina water, GenX raising concerns about its accumulation organisms, both wild cultured, could be pathway for human exposure. To examine potential exposure, tilapia (Oreochromis mossambicus) fingerlings were dosed with up 96 h fresh (0 ppt) or brackish (16 water determine uptake bioconcentration. Depuration values also determined after exposure followed by without Bioconcentration was decreasing order plasma > liver carcass muscle, higher distribution muscle. Muscle have highest half-life (1278 h) (532 h), (106 (152 h). rate depuration positively affected salinity. As bioconcentration all tissues increased increasing salinity, this may raise marine